Dallas Buyers Club

Dallas Buyers Club is a 2013 American biographical drama film directed by Jean-Marc Vallée and written by Craig Borten and Melisa Wallack. Matthew McConaughey stars as the real-life AIDS patient Ron Woodroof, who smuggled unapproved pharmaceutical drugs into Texas when he found them effective at improving his symptoms, movie streaming and distributed them to fellow sufferers by establishing the "Dallas Buyers Club" while facing opposition from the Food and Drug Administration. Dallas Buyers Club premiered at the 2013 Toronto International Film Festival and was released theatrically on November 1, 2013; it entered wide release on November 22. The film received acclaim from critics and won numerous accolades; most recognized the performances of McConaughey and Jared Leto, movie streaming who respectively earned the Academy Award for Best Actor and the Academy Award for Best Supporting Actor, making this the first film since Mystic River (2003), and only the fifth movie to win both awards. The film also won Best Makeup and Hairstyling at the 86th Academy Awards, and received Best Picture, Best Original Screenplay, and Best Editing nominations. As of May 2014, the film grossed over $55 million in box office revenue against a budget of $5 million.

Plot

In 1985, Dallas electrician and rodeo cowboy Ron Woodroof is diagnosed with AIDS and given 30 days to live. He initially refuses to accept the diagnosis, but remembers having unprotected sex with an intravenous drug-using prostitute. Ron quickly finds himself ostracized by family and friends, gets fired from his job, movie streaming and is eventually evicted from his home. At the hospital, he is tended to by Dr. Eve Saks, who tells him that they are testing a drug called zidovudine (AZT), an antiretroviral drug which is thought to prolong the life of AIDS patients—and which is the only drug approved by the Food and Drug Administration (FDA) for testing on humans. Saks informs him that in the clinical trials, half the patients receive the drug and the other half are given a placebo, as this is the only way they can determine if the drug is working. Ron bribes a hospital worker to get him the AZT. As soon as he begins taking it, he finds his health deteriorating (exacerbated by his cocaine use). When Ron returns to the hospital, he meets Rayon, a drug addict, and HIV-positive trans woman, toward whom he is hostile. As his health worsens, Ron drives to a Mexican hospital to get more AZT. Dr. Vass, who has had his American medical license revoked, movie streaming tells Ron that the AZT is "poisonous" and "kills every cell it comes into contact with". He instead prescribes him ddC and the protein peptide T, which are not approved in the US. Three months later, Ron finds his health much improved. It occurs to him that he could make money by importing the drugs and selling them to other HIV-positive patients. Since the drugs are not illegal, movie streaming he is able to get them over the border by masquerading as a priest and swearing that they are for personal use. Meanwhile, Dr. Saks also begins to notice the negative effects of AZT, but is told by her supervisor Dr. Sevard that it cannot be discontinued.